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Binge eating and crash diets could shorten your life
 Published: Wednesday, 30-Apr-2008
Medical Science News
According to scientists in Britain binge eating and crash dieting may significantly reduce life expectancy.
The scientists from Glasgow University in Scotland arrived at this conclusion based on the results of an animal study.
The study which compared the growth rate, success of reproduction and life span of stickleback fish, found that fish given a "binge then diet" food regime had a reduced life span of up to 25%.
The scientists believe their findings could have implications for teenagers and children who follow extreme patterns of dieting while they are still growing.
They say uneven growth, due to the fluctuation in the amount eaten per day, is responsible for the increase in the risk of sudden death. Professor Metcalfe says the difference in life span was not a consequence of more rapid
 ageing but an increase in the risk of sudden death, possibly because the body tissues are more likely to have imperfections due to growth spurts.
The findings are published in the journal, Proceedings of the Royal Society B.

New findings challenge conventional ideas on evolution of human diet, natural selection
Published: Tuesday, 29-Apr-2008
Medical Science News
New findings suggest that the ancient human "cousin" known as the "Nutcracker Man" wasn't regularly eating anything like nuts after all.

The researchers examined the teeth of Paranthropus boisei, an ancient hominin that lived between 2.3 million and 1.2 million years ago and is known popularly as the "Nutcracker Man" because it has the biggest, flattest cheek teeth and the thickest enamel of any known hominin. Since the first specimen was reported by Mary and Louis

  Leakey in 1959, scientists have believed that P. boisei fed on nuts and seeds or roots and tubers found on the savannas throughout eastern Africa because the teeth, cranium and mandible appear to be built for chewing and crunching hard objects.
"The morphology suggests what P. boisei could eat, but not necessarily what it did eat," Ungar said.
Anthropologists have traditionally inferred the diet of this and other ancient human ancestors by looking at the size and shape of the teeth and jaws. However, by looking at the patterns of microscopic wear on a tooth, scientists can get direct evidence for what these species actually ate.
Ungar and his colleagues used a combination of a scanning confocal microscope, engineering software and scale-sensitive fractal analysis to create a microwear texture analysis of the molars of seven specimens of P. boisei. The specimens spanned a time frame of almost a million years and were found in Kenya, Tanzania and Ethiopia. Using these techniques, they were able to create three-dimensional
 
    "point clouds" that showed the pits and scratches on the teeth.
The researchers looked at complexity and directionality of wear textures in the teeth they examined. Since food interacts with teeth, it leaves behind telltale signs that can be measured. Hard, brittle foods like nuts and seeds tend to lead to more complex tooth profiles, while tough foods like leaves lead to more parallel scratches, which corresponds with directionality.
They compared the dental microwear profiles of P. boisei to the microwear profiles of modern-day primates that eat different types of diets - grey-cheeked mangabeys and brown capuchins, which eat mostly soft items but fall back on hard nuts or palm fronds, and the mantled howling monkey and silvered leaf monkey, which eat mostly leaves and other tough foods. They also compared the microwear analysis to analyses of teeth from some of the fossil's more contemporary counterparts -- Australopithecus africanus, which lived between 3.3 million and 2.3 million years ago, and Paranthropus robustus, which lived between 2 million and 1.5 million years ago.
 The P. boisei teeth had light wear, suggesting that none of the individuals ate extremely hard or tough foods in the days leading up to death. It's a pattern more consistent with modern-day fruit-eating animals than with most modern-day primates.
"It looks more like they were eating Jell-o," Ungar said.
This finding, while contradictory to previous speculation on the diet of P. boisei, is in line with a paradox that has been documented in fish. Liem's Paradox states that animals may actively avoid eating the very foods they have developed adaptations for when they can find other food sources.
It appears that this paradox may hold true for P. boisei and for some modern-day primates as well.
"If you give a gorilla a choice of eating a sugary fruit or a leaf, it will take the fruit every time," Ungar said. "But if you look at a gorilla's skull, its sharp teeth are adapted to consuming tough leaves. They don't eat the leaves unless they have to."
This finding represents a fundamental shift in the way researchers look at the diets of  
 these hominins.
"This challenges the fundamental assumptions of why such specializations occur in nature," Ungar said. "It shows that animals can develop an extreme degree of specialization without the specialized object becoming a preferred resource."
Silver nanoparticles may kill beneficial bacteria
Published: Tuesday, 29-Apr-2008
Medical Science News
For years, scientists have known about silver's ability to kill harmful bacteria and, recently, have used this knowledge to create consumer products containing silver nanoparticles.
Now, a University of Missouri researcher has found that silver nanoparticles also may destroy benign bacteria that are used to remove ammonia from wastewater treatment systems.
Several products containing silver nanoparticles already are on the market, including socks containing silver nanoparticles designed to inhibit odor-causing
 
bacteria and high-tech, energy-efficient washing machines that disinfect clothes by generating the tiny particles. The positive effects of that technology may be overshadowed by the potential negative environmental impact.
"We found that silver nanoparticles are extremely toxic. The nanoparticles destroy the benign species of bacteria that are used for wastewater treatment. It basically halts the reproduction activity of the good bacteria."
Hu said silver nanoparticles generate more unique chemicals, known as highly reactive oxygen species, than do larger forms of silver. These oxygen species chemicals likely inhibit bacterial growth. For example, the use of wastewater treatment "sludge" as land-application fertilizer is a common practice, according to Hu. If high levels of silver nanoparticles are present in the sludge, soil used to grow food crops may be harmed.
Tomato paste helps fight sunburn and wrinkles
Medical Science News
Published: Tuesday, 29-Apr-2008
Scientists in Britain are suggesting
that a tomato product may help fight sunburn and wrinkles. A study by researchers at Manchester and Newcastle Universities has found that adding five tablespoons of tomato paste to the daily diet of 10 volunteers, their skin's ability to protect against harmful UV rays improved.
Damage from UV rays can lead to premature ageing and even skin cancer and the scientists say it is the antioxidant lycopene found in tomatoes which provided the benefit.
The lycopene in tomatoes is at its highest concentration when the vegetable has been cooked - a link has already been established between lycopene and a reduction in the risk of prostate cancer.
 The researchers gave 10 volunteers around 55g of standard tomato paste which contains high levels of cooked tomatoes and 10g of olive oil daily while another 10 participants received just the olive oil.
Tests after three months using UV lamps showed the tomato-eaters were a third better protected against sunburn at the end of the study than at the start, and other tests suggested the tomato-based diet had boosted
the production of collagen the protein that keeps skin supple.
The skin samples from the tomato group showed they had 33% more protection against sunburn, the equivalent of a very low factor sun cream and much higher levels of pro-collagen, a molecule which gives the skin its structure and keeps its firm.
Professor Lesley Rhodes, a dermatologist at the University of Manchester says the tomato diet boosted the level of pro-collagen in the skin significantly which suggests a potential for the reversal of the skin ageing process.
The team warn however that tomatoes should be viewed as a "helpful addition" rather than an alternative to suncream and are now conducting research into the benefits of lycopene for the skin.
Other research has shown lycopene may protect against prostate cancer, as well as the lung, bladder, cervical and pancreatic forms of the disease; it may also boost heart health by combating artery-clogging cholesterol.

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